In a groundbreaking study recently published in Cell Host & Microbe, researchers from the Georgia State University Institute for Biomedical Sciences have unveiled an important connection between the composition of gut microbiota and the severity of respiratory viral infections (RVIs). The paper, titled “Intestinal Microbiota Programming of Alveolar Macrophages Influences Severity of Respiratory Viral Infection,”…
In a groundbreaking paper published in Science, a team of scientists from the California Institute of Technology (Caltech) has unveiled a remarkable achievement in the realm of enzymatic evolution. Titled “Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes,” the research introduces a novel approach to manipulating bacterial cytochrome P450 variants for breaking silicon-carbon bonds…
In a groundbreaking study recently published in Nature Communications, scientists from Northwestern University and various research institutions have shed light on a previously unrecognized connection between survival genes, neurotoxicity, and the onset of Alzheimer’s disease and aging. The paper, titled “Death induced by survival gene elimination is correlated with neurotoxicity in Alzheimer’s disease and aging,”…
In the ever-evolving landscape of molecular biology, a novel method named KARR-seq (Kethoxal-Assisted Rapid RNA sequencing) has emerged as a game-changer, propelling our understanding of RNA structures and interactions to new heights. Developed as a groundbreaking tool, KARR-seq is revolutionizing the field by providing researchers with unprecedented insights into the intricate world of RNA. Understanding…
In a remarkable stride towards advancing cancer therapeutics, researchers at City of Hope have unveiled groundbreaking findings in their preclinical study titled “Therapeutic Application of Human Type 2 Innate Lymphoid Cells via Induction of Granzyme B-Mediated Tumor Cell Death.” This research signals a potential breakthrough in the fight against cancer, revealing the capability of human…
In a strategic move to fortify its global presence and enhance pharmaceutical production capabilities, Boehringer Ingelheim, the pharmaceutical giant, has announced the further expansion and upgrade of its production site in Koropi, Greece. With an investment of 120 million euros, Boehringer Ingelheim is set out to increase its manufacturing capacities for new and existing drugs,…
In a significant stride towards advancing precision medicine, GlaxoSmithKline (GSK) has announced a three-year collaboration agreement with Tempus, a leader in data-driven precision medicine, to get access to Tempus’ AI-enable platform, including its library of de-identified patient data. This partnership aims to harness the power of data and artificial intelligence to accelerate research and development…
In a significant leap forward in the ongoing battle against drug-resistant cancers, Gradalis, a forefront player in personalized cancer immunotherapy, has unveiled promising results for its innovative candidate, GRAD1405 bi-shRNAi. This groundbreaking therapeutic has exhibited a positive impact on three key KRAS mutations prevalent in drug-resistant lung, colon, and pancreatic cancers. The emergence of such…
In a groundbreaking development, a team of scientists have discovered a new class of antibiotics using artificial intelligence, marking the first such breakthrough in over six decades. This momentous achievement stems from the recent publication of the paper titled “Discovery of a Structural Class of Antibiotics with Explainable Deep Learning.” The findings promise to be…